Peptide entry
Melanotan 1
Also known as: Afamelanotide context
Evidence / context
Clinical note: melanocortin context is formulation-dependent.
Available vial formats
- Conservative 250 mcg per injection once daily or every other day (5 units per injection)
- Standard 250-500 mcg per injection once daily during loading (5-10 units per injection)
- Aggressive 1.0 mg once daily during short loading (20 units per injection) only if clearly tolerated
- Cycle length 2-6 weeks loading, then maintenance as needed.
- Best timing Evening if nausea occurs.
Reconstitution
- Swab vial tops with alcohol
- Add 2.0 mL bacteriostatic water slowly
- Swirl gently - do not shake
- Refrigerate 2-8 C
Dosing, cycle & timing
- Conservative 250 mcg per injection once daily or every other day (5 units per injection)
- Standard 250-500 mcg per injection once daily during loading (5-10 units per injection)
- Aggressive 1.0 mg once daily during short loading (20 units per injection) only if clearly tolerated
- Cycle length 2-6 weeks loading, then maintenance as needed.
- Best timing Evening if nausea occurs.
Timing: Use with deliberate UV strategy rather than random exposure. Do not assume the peptide replaces sun protection.
Support / expected effects
- Pigmentation/tanning response support.
- More targeted pigmentation context than libido-oriented melanocortin use.
- Requires careful skin monitoring during loading and maintenance.
Side effects / tolerability
- Nausea
- Flushing
- Darkening of freckles or moles
Notes
- Clinical note: regulated afamelanotide context is formulation-specific.
- Keep separate from PT-141 or MT-II.
- Monitor existing moles, freckles, and any new or changing pigmented lesions; pause and seek dermatologic review for concerning changes.
Practical tips
- Start low and watch pigment changes closely
- Use sunscreen and skin surveillance anyway
- If nausea is strong, reduce dose or move later
Storage
Refrigerate 2-8 C after mixing and use within the product-specific beyond-use window.
Related peptides
Related goal guides
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FAQ
What is Melanotan 1 explored for?
Pigmentation/tanning response support. More targeted pigmentation context than libido-oriented melanocortin use. Requires careful skin monitoring during loading and maintenance.
How is Melanotan 1 reconstituted?
1) Swab vial tops with alcohol 2) Add 2.0 mL bacteriostatic water slowly 3) Swirl gently - do not shake 4) Refrigerate 2-8 C
What is a typical cycle length for Melanotan 1?
2-6 weeks loading, then maintenance as needed.
How are doses measured in syringe units here?
Units mean U-100 insulin-syringe gradations (1 mL = 100 units), not International Units. Use the calculator only when the vial concentration and injection volume are known.