Peptide entry
MOTS-c
Evidence / context
Evidence: Limited. Mitochondrial and metabolic-support use is best judged by repeatable response.
Available vial formats
- Conservative 2.5 mg per injection, 2-3x/week (19 units per injection)
- Standard 5 mg per injection, 2-3x/week (38 units per injection)
- Aggressive 5 mg per injection once daily short-term only (38 units per injection), or 10 mg per injection 1-2x/week only if clearly tolerated (75 units per injection)
- Cycle length 2-6 weeks; keep aggressive blocks short and reassess.
- Best timing Morning or pre-workout.
- Conservative 2.5 mg per injection, 2-3x/week (50 units per injection)
- Standard 5 mg per injection, 2-3x/week (100 units per injection)
- Aggressive 5 mg per injection once daily short-term only (100 units per injection), or 10 mg per injection 1-2x/week only if clearly tolerated (200 units per injection)
- Cycle length 2-6 weeks; keep aggressive blocks short and reassess.
- Best timing Morning or pre-workout.
Reconstitution
- Swab vial tops with alcohol
- Draw 3.0 mL bacteriostatic water
- Inject slowly down vial wall (don't blast powder)
- Gently swirl - do not shake
- Rest 5-10 min to dissolve
- Refrigerate 2-8 C
Dosing, cycle & timing
- Conservative 2.5 mg per injection, 2-3x/week
- Standard 5 mg per injection, 2-3x/week
- Aggressive 5 mg per injection once daily short-term only, or 10 mg per injection 1-2x/week only if clearly tolerated
- Cycle length 2-6 weeks; keep aggressive blocks short and reassess.
- Best timing Morning or pre-workout.
Timing: Avoid late evening if it causes stimulation or sleep disruption.
Support / expected effects
- Insulin sensitivity/fuel partitioning support.
- Often reported: endurance/recovery.
- Fat oxidation/metabolic flexibility support.
Side effects / tolerability
- Warmth/flushing.
- Mild nausea.
- Fatigue if overdosed.
Practical tips
- Start low if nausea/fatigue occurs.
- Pairs well with NAD+ and L-carnitine.
- Consistency > daily high dose for most.
- 10 mg and 40 mg vials use the same biological dose range; vial size only changes concentration and units draw.
Storage
Refrigerated: ~45-60 days.
Related peptides
Related goal guides
Related categories
FAQ
What is MOTS-c explored for?
Insulin sensitivity/fuel partitioning support. Often reported: endurance/recovery. Fat oxidation/metabolic flexibility support.
How is MOTS-c reconstituted?
1) Swab vial tops with alcohol 2) Draw 3.0 mL bacteriostatic water 3) Inject slowly down vial wall (don't blast powder) 4) Gently swirl - do not shake 5) Rest 5-10 min to dissolve 6) Refrigerate 2-8 C
What is a typical cycle length for MOTS-c?
2-6 weeks; keep aggressive blocks short and reassess.
How are doses measured in syringe units here?
Units mean U-100 insulin-syringe gradations (1 mL = 100 units), not International Units. Use the calculator to convert a dose into the exact draw for your vial and water amount.